Reuse-Based Test Recommendation in Software Engineering

Still today, the development of effective and high-quality software tests is an expensive and very labor intensive process. It demands a high amount of problem awareness, domain knowledge and concentration from human software testers. Therefore, any technology that can help reduce the manual effort involved in the software testing process -- while ensuring at least the same level of quality -- has the potential to significantly reduce software development and maintenance costs. In this dissertation, we present a new idea for achieving this by reusing the knowledge bound up in existing tests. Over the last two decades, software reuse and code recommendation has received a wide variety of attention in academia and industry, but the research conducted in this area to date has focused on the reuse of application code rather than on the reuse of tests. By switching this focus, this thesis paves the way for the automated extraction of test data and knowledge from previous software projects. In particular, it presents a recommendation approach for software tests that leverages lessons learned from traditional software reuse to make test case reuse suggestions to software engineers while they are working. In contrast to most existing testing-assistance tools, which provide ex post assistance to test developers in the form of coverage assessments and test quality evaluations, our approach offers an automated, proactive, non-intrusive test recommendation system for efficient software test development

Mobility in a Globalised World

The term mobility has different meanings in the following academic disciplines. In economics, mobility is the ability of an individual or a group to improve their economic status in relation to income and wealth within their lifetime or between generations. In information systems and computer science, mobility is used for the concept of mobile computing, in which a computer is transported by a person during normal use. Logistics creates, by the design of logistics networks, the infrastructure for the mobility of people and goods. Electric mobility is one of today’s solutions from engineering perspective to reduce the need of energy resources and environmental impact. Moreover, for urban planning, mobility is the crunch question about how to optimize the different needs for mobility and how to link different transportation systems. The conference “Mobility in a Globalised World” took place in Iserlohn, Germany, on September 14th – 15th, 2011. The aim of this conference was to provide an interdisciplinary forum for the exchange of ideas among practitioners, researchers, and government officials regarding the different modes of mobility in a globalised world, focusing on both domestic and international issues. The proceedings at hand document the results of the presentations and ensuing discussions at the conference

Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe

Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies

There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR gamma:Peroxisome proliferator-activated receptor, NF kappa B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2 alpha:Elongation initiation factor 2 alpha). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT(1)R axis (AT(1)R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Reuse-Based Test Recommendation in Software Engineering

Still today, the development of effective and high-quality software tests is an expensive and very labor intensive process. It demands a high amount of problem awareness, domain knowledge and concentration from human software testers. Therefore, any technology that can help reduce the manual effort involved in the software testing process -- while ensuring at least the same level of quality -- has the potential to significantly reduce software development and maintenance costs. In this dissertation, we present a new idea for achieving this by reusing the knowledge bound up in existing tests. Over the last two decades, software reuse and code recommendation has received a wide variety of attention in academia and industry, but the research conducted in this area to date has focused on the reuse of application code rather than on the reuse of tests. By switching this focus, this thesis paves the way for the automated extraction of test data and knowledge from previous software projects. In particular, it presents a recommendation approach for software tests that leverages lessons learned from traditional software reuse to make test case reuse suggestions to software engineers while they are working. In contrast to most existing testing-assistance tools, which provide ex post assistance to test developers in the form of coverage assessments and test quality evaluations, our approach offers an automated, proactive, non-intrusive test recommendation system for efficient software test development

Reuse-Based Test Recommendation in Software Engineering

Still today, the development of effective and high-quality software tests is an expensive and very labor intensive process. It demands a high amount of problem awareness, domain knowledge and concentration from human software testers. Therefore, any technology that can help reduce the manual effort involved in the software testing process -- while ensuring at least the same level of quality -- has the potential to significantly reduce software development and maintenance costs. In this dissertation, we present a new idea for achieving this by reusing the knowledge bound up in existing tests. Over the last two decades, software reuse and code recommendation has received a wide variety of attention in academia and industry, but the research conducted in this area to date has focused on the reuse of application code rather than on the reuse of tests. By switching this focus, this thesis paves the way for the automated extraction of test data and knowledge from previous software projects. In particular, it presents a recommendation approach for software tests that leverages lessons learned from traditional software reuse to make test case reuse suggestions to software engineers while they are working. In contrast to most existing testing-assistance tools, which provide ex post assistance to test developers in the form of coverage assessments and test quality evaluations, our approach offers an automated, proactive, non-intrusive test recommendation system for efficient software test development

Reuse-Based Test Recommendation in Software Engineering

Still today, the development of effective and high-quality software tests is an expensive and very labor intensive process. It demands a high amount of problem awareness, domain knowledge and concentration from human software testers. Therefore, any technology that can help reduce the manual effort involved in the software testing process -- while ensuring at least the same level of quality -- has the potential to significantly reduce software development and maintenance costs. In this dissertation, we present a new idea for achieving this by reusing the knowledge bound up in existing tests. Over the last two decades, software reuse and code recommendation has received a wide variety of attention in academia and industry, but the research conducted in this area to date has focused on the reuse of application code rather than on the reuse of tests. By switching this focus, this thesis paves the way for the automated extraction of test data and knowledge from previous software projects. In particular, it presents a recommendation approach for software tests that leverages lessons learned from traditional software reuse to make test case reuse suggestions to software engineers while they are working. In contrast to most existing testing-assistance tools, which provide ex post assistance to test developers in the form of coverage assessments and test quality evaluations, our approach offers an automated, proactive, non-intrusive test recommendation system for efficient software test development